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        This is the best solution for the long-term treatment of kidney disease. It provides the best long-term
        results, in terms of patient and graft survival, and commonly means the patient does not need an extended
        period of dialysis. The disadvantage is that a live healthy person needs to undergo a very significant
        operation to have one of their kidneys removed. This procedure carries risks to the donor. These risks can
        also include the occasional risk of the donor dying in the process. This is extraordinarily rare but does
        happen about one time in three thousand. There are a few
        essential rules that the donor must fulfil before being
        considered a potential live related donor.
        l They must be a compatible blood group
        l They must be fully informed of the risk and benefits of the
           procedure, and be willing, of their own free will, to undergo
           the procedure
        l They must be in perfect health
        l The final cross match test must be negative.
           The potential living donor will have to volunteer
        themselves and make contact themselves with the Transplant
        Office phone: 01-8528397. The donor will undergo a very
        extensive medical and psychological evaluation to determine
        that they are suitable. This will include a number of special
        investigations and examinations by an independent doctor.
           The one-year success rate of a living donor is about 95%                                   BOOK 4
                                                                                                     2nd Edition
        and, on average, a living donor kidney will last 16 years.
        However, if your donor is a ‘perfect match’, on average such a
        kidney will last 28 years.
           Please see Book 4 ‘Thinking About Donating a Kidney?’.

                                              TRANSPLANT MEDICINES

           Following the transplant, you will need to remain  pressure, and sometimes increase the risk of
        on transplant medicines for the rest of your life.    diabetes.
        The actual dose, that you take, will change from         Prograf is a powerful immuno-suppressant. It
        time to time, particularly in the early months. After  can, however, make you more susceptible to
        the transplant, they will be rapidly reduced. If you  infections. Other side-effects include skin cancer,
        ever stop taking the transplant medicines,            and other cancers, and, in the long-term, kidney
        you will lose your transplant kidney through          damage. Your doctor will try to achieve a balance
        rejection.                                            between using the lowest possible dose to avoid
           There are many transplant medicines, such as       rejection, and to minimise the risk of kidney
        Prednisilone, Prograf (Tacrolimus) and CellCept       damage and other side effects.
        (Mycophenolate Mofetil). These medications, while        CellCept is also a powerful immuno-suppressant.
        effective, cause a number of side effects.            It has many of the side effects of Prograf, but it
           Steroids can make you gain weight, become          does not damage the kidney. It can cause diarrhoea
        puffy around the face, increase your blood            and stomach upset initially.

        P.30 Haemodialysis and Peritoneal Dialysis – A Guide for Patients
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