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WHAT CAN I DO IF MY LIVING DONOR IS NOT A MATCH?


        If you have a living donor willing to donate a kidney  into a paired kidney exchange programme with
        to you, but they are not a match because of blood     others in a similar predicament.
        group or antibody reasons, there are a number of        This is where your donor gives their kidney to a
        possibilities.                                        compatible recipient and the recipient’s donor gives
           If the recipient  is not highly sensitised         you their kidney. Obviously, this depends on both
        (PGEN<70%) and has a blood group incompatible         kidneys being matched and suitable for
        donor, the best option to consider would be to enter  transplantation.

                                               EXAMPLE 1
        Mr. Jones is blood type A and wants to donate a kidney to Ms. Jones who is blood type B.
        Mr. and Mrs. Smith, have opposite circumstance (blood type B donor who wants to donate
        to blood type A recipient).
           The donor kidneys could be exchanged and both groups would undergo a living donor
        and transplant procedure.



                     Donor                                                             Donor


                 Mr. Jones                                                         Mr. Smith


               (Blood Type A)                                                     (Blood Type B)







                 Recipient                                                         Recipient


                Ms. Jones                                                          Ms. Smith

               (Blood Type B)                                                     (Blood Type A)






                       IT IS IMPORTANT TO POINT OUT THAT SUCH AN ARRANGEMENT IS NOT YET

                       AVAILABLE IN IRELAND BUT YOUR TRANSPLANT TEAM MIGHT BE ABLE TO
                       ARRANGE FOR YOU TO BE REFERRED TO THE UK, WHERE SUCH PROCEDURES
                       HAVE TAKEN PLACE.


                                                                                It is however, important to
                                    EXAMPLE 2                                   appreciate that some patients
          If, on the other hand, the recipient  is highly sensitised            with high antibody levels may
          (PGEN>70%) and they have an ABO incompatible donor                    have to wait a very long time to
          but well HLA-matched donor, it might be possible to enter             get a suitable donor match.
          into a programme to remove ABO antibodies and proceed                 Effective technology does not
          with the kidney transplant, across imcompatible blood                 currently exist to remove HLA
          groups. You nephrologist will discuss this in more detail if          antibodies to allow successful
          necessary.                                                            transplantation.




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