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        Kidney transplantation is a major surgical procedure
        with a success rate of about 95%. That is, 95% of
        kidneys transplanted will be functioning one year
        after the surgery.
           Viewed another way, about 5 people in a 100 will
                      not have a successful outcome from
                            kidney    transplantation.    In
            “Kidney            general, about 3 patients in
       transplantation          100 will die, either during
                                 the operation, or shortly
     is a major surgical
                                 afterwards. Pre-operation
      procedure with a           testing, minimises these
       success rate of           risks; nonetheless, you

         about 95%.”           should be aware that there
                             are significant risks associated
                          with transplant surgery.
           Other risks associated with transplant surgery will be discussed later in this book, but the transplant
        medicines necessary for the transplant to function, can cause side effects including diabetes, increased
        risk of infection, weight gain, increased risk of skin cancer and, rarely, lymphoma, (a form of cancer). There
        is also approximately a 10% risk of transplant rejection, which can be treated with courses of medicine,
        but still represents a risk to your new kidney. By following your doctor’s instructions, and having regular
        medical check-up’s you can help minimise the risk of your new kidney failing.

                                               The outcome                   NEPHRON DOSING
                                             of kidney             The nephron is the functional unit of the
                                                                   kidney where all filtration takes place. A
                                             needs to be           healthy kidney has approximately one million
                                             compared with
                                                                   nephrons. The goal of transplantation is to
                                             the alternative,      deliver the “healthiest” kidney to the
                                             which is many
                                             years of dialysis.       In a small number of cases, usually if the
                                             In general, kidney
                                                                   donor is an older individual, both kidneys are
                                            transplantation        transplanted into a single recipient to
                  results in more than doubling of life
                                                                   maximise the number of nephrons delivered.
        expectancy, when compared to remaining on dialysis.        This type of transplant is called “nephron
           Deceased donor kidney transplants function for an
        average of 15 or 16 years. A live donor transplant            A kidney is placed on either side of the
        functions for an average of 17 to 20 years and a
                                                                   lower abdomen resulting in two scars. This
        full-house matched live donor kidney transplant            operation takes longer than a single
        functions for an average of 32 years.
                                                                   transplant and the recipient has a longer
                                                                   hospital stay. These kidneys can also be
                  “The outcome of kidney                           ‘slow to start.’ The decision to carry out a

               transplantation needs to be                         nephron dosing transplant is made on a
             compared with the alternative,                        case-by-case basis and is discussed with the
                                                                   potential recipient prior to surgery
            which is many years of dialysis.”

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